Skip Navigation

Student Research Projects

Polyelectrolyte Multilayer Films: UV-visible Studies of Methylene Blue Loading and Rates of Release

Student Alison Washington '15
Faculty Mentor(s) Dr. Kevin Kittredge
Department Chemistry
Course Independent Research

Abstract

Polyelectrolyte multilayered thin films have also shown significant potential as candidates for sustained and controlled drug delivery systems. However, the feasibility of their applications strongly depends on their permeability and their stability under biologically and/or physically relevant conditions. Understanding the permeability of cross-linked films will provide insight into adjusting the organization and processing parameters for controlling release rates. Hyperbranched PAA/PAH (poly(acrylic acid) / poly(allylamine hydrochloride)) films have been synthesized in a layer-by-layer fashion. We have recently reported how the heat-induced cross-linking of PAA/PAH films affects both MB loading capacity and release rate into solution. UV-visible spectroscopy was used to obtain both quantitative and qualitative data for MB loading, releasing, and structural rearrangements within the films. Furthermore, our studies showed that loading MB into films is a function of the curing temperature.

Conferences

Presented at the ACS 16th annual Tidewater Research Poster Session, Christopher Newport University

Awards

2013 Virginia Foundation for Independent Colleges
Summer Undergraduate Science Research Fellowship

 

Website Comments/Feedback

©2014 Virginia Wesleyan College